Anti-Aging MHI

Any advanced optimization strategy inevitably confronts the limitations of chronological age. Enhanced by targeted supplementation, specifically senolytics, these potent peptides act as conductors, synchronizing your body’s innate rhythms to restore youthfulness at the cellular level. They are designed to stimulate cellular renewal & resilience, which play a pivotal role in influencing biological age & rejuvenation.

FOX-O4

505 amino acids & half-life varies

FOXO4 (Forkhead box protein O4) is a transcription factor peptide involved in regulating various cellular processes, including cell cycle, DNA repair, apoptosis, and stress response. This peptide’s antagonistic design selectively induces apoptosis of senescent cells, which are first to become cancerous. In addition to reversing signs of aging, FOXO4 also aids tumor suppression. Recent studies suggest its use in regenerative therapies targeting age-related diseases.

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Epitalon

4 amino acids & half life varies

This peptide was discovered in the 1980s by Professor Vladimir Khavinson, a Russian scientist who serves as Director of the Saint Petersburg Institute of Bioregulation and Gerontology. Epitalon is known for its anti-aging and health effects. Studies show it increases DNA telomere length, playing a key role in extending longevity and preventing age-related diseases such as cancer, heart disease, and dementia. It has also shown to regenerate tissues and restore function to organs in disrepair.

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GHK-CU

3 amino acids with a copper ion (Cu) & half-life varies

In the realm of skin health, clinical studies demonstrate this peptide’s capacity to stimulate collagen and elastin production. When integrated into cosmetic formulations, it enhances skin texture and firmness. For injuries and tears, GHK-CU has been studied for its benefits in wound healing, tendons, and ligaments by stimulating collagen production and tissue regeneration at the injured site, commonly used together with BPC-157 and/or TB-500.

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SS-31 (Elamipretide)

4 amino acids & has a half life of roughly 1 hour

Its a 4-amino acid peptide that targets the mitochondria — the energy-producing engines inside your cells — and protects them from internal damage caused by oxidative stress. It binds to the inner mitochondrial membrane, stabilizes it, reduces electron leakage and harmful free radical production, allowing cells to generate cleaner, more efficient energy. What it means for you: More energy, better focus, faster recovery, and slower aging — by repairing and protecting your body’s power source.

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Klotho

15-30 amino acids & has a 30–60 minute half-life

Is a powerful anti-aging protein. It stimulates longevity genes, which decline naturally with age. It supports brain, kidney, and metabolic function, while reducing inflammation and oxidative stress. What it means for you: Sharper cognition, healthier organ function, improved metabolic efficiency, and increased healthspan — by turning on your body’s natural longevity programming. Emerging research also links this protein to enhanced cellular repair and mitochondrial health.

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OS-01 (ATX-304) – oral form

Small molecule therapeutic & unknown half-life

OS-01 is a direct pan-AMPK activator, meaning it stimulates all forms of AMPK—the master switch for cellular energy. As we age, AMPK activity declines, slowing metabolism, fat burning, and cellular repair. OS-01 restores this function by preventing deactivation of AMPK and acting as a mild mitochondrial uncoupler, which boosts energy output. This dual action helps improve glucose control, enhance fat metabolism, support cardiovascular performance, reduce inflammation.

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